Advantage®II Flea Treatment for Cats

Advantage®II Flea Treatment for Cats
Crosshairs icon showing Advantage®II treats fleas

Treats: Fleas, flea eggs, flea larvae 

Advantage®II treats cats and kittens from 8 weeks

Pet type: Cats and kittens over 8 weeks of age 

Advantage®II for cats is a topical treatment

Formulation: Topical  

Calendar icon showing advantage dosage is once a month

Suggested frequency: Every 4 weeks 

Additional Info & Benefit:
Advantage®II Large Cat
Advantage®II Kitten
Advantage®II for cats’ sizes and packaging
Advantage®II protects against flea infestations with regular flea treatment

A flea infestation can make your cat’s life miserable. On top of the irritation and itchiness, fleas can also lead to serious health problems.

Some cats have allergies to flea saliva. In these cases, just a few flea bites can cause flea allergy dermatitis, triggering severe itching and sore skin. Fleas can also lead to anemia (if a flea infestation is severe) and even a tapeworm infection, should your cat swallow an infected flea while grooming. And because fleas feed on all red-blood mammals, they can also prey on humans.

It’s important to remember that the fleas on your cat are only part of the problem. The adult fleas visible on your cat account for only five per cent of all the fleas present in an infestation. The rest are lurking as eggs, larvae and pupae, which may be hidden and scattered throughout your home.

Regular flea prevention will help protect your cat’s health and well-being and prevent flea infestation in your home.

Why choose Advantage®II?
Up to 28 days of protection
Kills fleas through contact
Suitable for use on kittens and adult cats
Advantage®II is a fast and effective flea treatment
Parasites treated by Advantage II for cats
Advantage®II is a fast and effective flea treatment

Advantage®II is a topical flea treatment that contains an active ingredient which works to kill fleas through contact.

Applied as drops to the skin, the active ingredient in Advantage®II spreads throughout the skin quickly and kills fleas through contact. Unlike some other treatments available (for example, those available in pill form), your cat doesn’t have to be bitten for the treatment to work.

Advantage®II kills fleas within two hours and remains effective for up to four weeks.

How does Advantage®II work?

Advantage®II is not absorbed into the bloodstream. When applied to the back of your cat’s neck it remains locked in the oils of the cat’s skin and quickly spreads across the entire skin surface. The treated coat and skin results in the paralysis and death of adult fleas, flea eggs, and flea larvae.

Advantage®II not only kills adult fleas through contact, the product also contains the insect growth regulator pyriproxyfen which is distributed into the home on the fur and skin shed by the cat. This prevents flea eggs and larvae from developing into the next stage of the flea life cycle, effectively killing them.

How to Apply to Your Cat

Advantage®II comes in a pre-measured applicator tube appropriate for your cat’s weight. Once applied, the product spreads on the skin to provide full-body flea protection on contact.

How to apply Advantage®II step 1: remove collar before application
Step 1: Remove collar prior to application.
Remove one applicator tube from the package, hold it upright and pull the cap off.
Step 2: Hold the applicator tube upright and pull the cap off.
How to apply Advantage®II step 3: Use the reversed cap to pierce and twist off the seal from the tube.
Step 3: Place the reversed cap on the tube and twist to break the seal.
How to apply Advantage®II step 4: part your cat’s hair at the base of the skull until the skin is visible.
Step 4: Part your cat’s fur at the base of the skull until the skin is visible.
How to apply Advantage®II step 5: entire tube applied onto cat’s neck
Step 5: Apply entire tube onto the skin.
Advantage®II for Cats FAQs
How do I apply Advantage®II?

Step 1: Remove collar prior to application.

Step 2: Hold the applicator tube upright and pull the cap off.

Step 3: Place the reversed cap on the tube and twist to break the seal.

Step 4: Part your cat’s fur until the skin is visible. The treatment needs to be applied to the back of your cat’s neck at the base of the skull, high enough so your cat can’t lick it off.

Step 5: Place the tip of the tube on the skin and squeeze it firmly several times to empty the contents directly onto the skin. Do not rub the product in. Allow it to dry naturally. From this application site, the treatment will then spread throughout the rest of your pet’s skin for full protection.

Record treatment date and repeat monthly.

Note: only apply to intact skin. Keep recently treated animals separated for 12 hours so they can’t groom each other. It is recommended to keep your cat off leather furniture and wood floors while the product dries.

If you’re unsure how to apply Advantage®II treatment for cats, refer to the product information included in the pack or contact your veterinarian. Use the Advantage®II product that is suitable for the weight of your cat.

How does my cat get fleas?

There are several ways even the cleanest cat can get fleas:

  • Wild animals carry fleas, (including mice and rats, squirrels, groundhogs, rabbits, skunks, raccoons and foxes), and if they pass through your backyard, they can transfer fleas to your cat
  • Fleas can be passed on from other infested cats and dogs your cat comes into contact with while roaming your neighbourhood
  • Other pets in your home can be carriers, so make sure you keep all pets protected with a flea treatment
  • Cats can even catch fleas from you! You could unknowingly come into contact with fleas and transport them into your home and onto your pets.
What is the difference between how Advantage®II is applied and kills fleas, compared to oral flea products?

Advantage®II is a topical treatment so it’s applied to your pet’s skin and will kill fleas through contact. It does not require fleas to bite1.

Oral flea products, in contrast, are active in the bloodstream, which means fleas must bite your pet to be killed.

  • 1. Mehlhorn et al. Parasitol Res (2001) 87:198-207, information is regarding mode of action and is not intended to imply parasites can be completely stopped from biting.
How often should I use Advantage®II to protect my cat from fleas

Advantage®II flea treatment should be repeated every 4 weeks to protect your cat against fleas. Outdoors, fleas can’t survive temperatures under -1 Celsius for more than 5 days. Indoors, however, fleas can live indefinitely as long as they can find a red-blooded host to feed on. It may be best to err on the side of caution and continue your treatment in winter to keep fleas at bay. Your veterinarian can help you assess the level of flea risk in your region.

How long does Advantage®II last?

Advantage®II kills fleas within 24 hours of treatment and remains effective for up to four weeks.

If retreatment is necessary earlier than 4 weeks due to the scale of the infestation, do not treat your cat more frequently than once weekly.

Can I use Advantage®II on my kitten? 

Advantage®II Kitten should be used on kittens who are at least eight weeks old. Consult your veterinarian before using on a kitten who is still nursing.

Can I use Advantage®II on a pregnant or lactating cat?  

Consult your veterinarian before using this product, or any product, on pregnant or lactating cats.

Which Advantage®II product is right for my cat? 

Depending on your cat’s weight you can choose from Advantage®II Kitten, Small Cat or Large Cat.

What is included with each pack of Advantage®II? 

Every pack of Advantage®II contains 4 to 6 single-use tubes, and each tube protects against fleas for up to four weeks.

What are the active ingredients in Advantage®II? 

Advantage®II contains two active ingredients, imidacloprid and pyriproxyfen. Imidacloprid kills adult fleas through contact on your cat’s skin, fleas do not have to bite your pet to be killed1. Pyriproxyfen works as an insect growth regulator. Distributed into the home on fur and skin shed by the cat, pyriproxyfen prevents flea eggs and larvae from developing into the next stage of the flea life cycle.

When can I bathe my cat after applying Advantage®II? 

If you are bathing your pet (although bathing is not required) use an appropriate shampoo. A non-medicated shampoo designed for cats is fine. Baths can be given as often as once per month without affecting the performance of the product. If more than one bath is given, the product should be reapplied after the second bath.

Note: flea shampoo, medicated shampoos, human shampoo and dish detergents are not appropriate choices when managing fleas with Advantage®II as they may affect the performance of the product. Please wait 3 days between product application and bathing.

Can I use Advantage®II if my cat is on medication? 

Always consult your veterinarian before using Advantage®II if your cat is already taking other medication.

My cat is strictly an indoor cat. Do I still need to use Advantage®II? 

Yes. Fleas can unknowingly be brought into your home by you or other pets. Immature fleas in the form of eggs, larvae or pupae can remain dormant in your home until conditions are ideal for them to hatch and infest your pets. That’s why it’s important to also treat indoor pets.

I’ve only seen a couple of fleas on my cat. Should I still use Advantage®II? 

If you see any fleas on your cat, you’re only looking at five per cent of the total number that might be in your home.

For every fully-grown flea you spot there will be many more eggs, larvae and pupae hidden in carpets, bedding, furniture, floorboards and all kinds of nooks and crannies throughout your home. These will all soon hatch into new adult fleas. The best way to reduce the chances of flea infestations in your home is to use flea treatment regularly.

Only one of my pets appears to have fleas. Should I just treat the infected pet? 

It’s important to treat all pets in your household with a suitable flea product. Fleas multiply quickly, so once one pet is infested, it won’t be long before the fleas jump onto your other pets as well.

Can I split the tubes of Advantage®II between my cats? 

Do not split tubes between animals. Always follow the instructions on the packet carefully and give each cat the correct dosage for their weight. To ensure effective treatment, each cat should get their own tube of Advantage®II. If you’re unsure of how to apply Advantage®II, contact your veterinarian.

Do I need a prescription from my veterinarian to buy Advantage®II? 

Advantage®II is a non-prescription treatment which is available at pet specialty retailers, veterinarians, and online*.

*availability may vary by province

Can Advantage®II be used to treat Flea Allergy Dermatitis? 

Some cats are hypersensitive to flea saliva. This can cause an allergic reaction which leads to a skin condition called Flea Allergy Dermatitis (FAD). FAD can be highly uncomfortable for cats, causing them to compulsively scratch their irritated skin, often leading to hair loss and skin lesions.

If your veterinarian diagnoses your cat with Flea Allergy Dermatitis, Advantage®II can be used as part of a flea treatment strategy. The active ingredient in Advantage®II for cats kills fleas through contact, meaning the fleas don’t have to bite your cat in order to be killed1.

What is the expiration date for Advantage®II? I can’t find an expiry date on the box.  

Advantage®II does not expire.

I have more questions about Advantage®II. Who can I contact? 

We recommend contacting your veterinarian or Bayer Canada toll-free at 1-888-663-5326 (9 a.m. – 5 p.m. EST).

How should I treat my home for fleas? 

If your cat does catch fleas, your home can quickly become infested. Fleas lay eggs on your pet, which then fall off into your home. These eggs hatch into larvae, which develop into pupae and then adult fleas, which emerge hungry to feed on any red-blooded mammal – including humans. These eggs, larvae and pupae can be found in carpets, bedding, furniture, floorboards and all kinds of nooks and crannies throughout your home.

Advantage®II contains pyriproxyfen, an insect growth regulator. Pyriproxyfen is distributed into the home on fur and skin shed by the pets and prevents flea eggs and larvae from developing into the next stage of the flea life cycle. It is not necessary to treat your home with sprays or other products if your pets are treated with Advantage®II and are allowed to roam your entire home.

You can, however, put a stop to the flea cycle even faster by washing your pet’s bedding in very hot water (and your bedding as well if your pet sleeps with you) and putting it in the dryer on a hot setting, if possible. Vacuuming your carpets and floors at least once a week can also encourage fleas to seek out the protection of a cat – who has already been treated with Advantage®II for cats.

For more in-depth tips about tackling flea infestations, read our essential guide to evicting fleas from your home.

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Advantage®II for cats packaging