Advantage®II Flea Treatment Dogs

Advantage®II Topical Flea Treatment for Dogs
Treats fleas

Treats: Fleas, Flea eggs, Flea larvae, Lice

Advantage®II treats dogs and puppies from 7 weeks

Pet type: Dogs and puppies over 7 weeks of age

Advantage®II is a topical treatment

Application type: Topical

Calendar icon showing Advantage®II dosage is once a month

Suggested frequency: Every 4 weeks

Additional Info & Benefit:
Advantage®II Large Dog
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Advantage®II Small Dog
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Advantage®II Dog Flea Treatment Range
Protect against flea infestations with regular treatment

Most dogs will pick up fleas at some point in their lives. In fact, fleas are one of the most common parasites your dog will encounter while on their walks.

You shouldn’t ignore fleas just because they are common. Female fleas can lay up to 40 eggs per day which can quickly lead to an infestation, both on your dog and in your home. Fleas aren’t fussy who they bite either. They’ll feed on the blood of any red-blooded mammal, including humans.

Bites from these parasites can cause much more than an itch for your dog. They can lead to more serious health problems like dermatitis, anemia (if a flea infestation is severe) and even a tapeworm infection, should your dog swallow an infected flea while grooming.

The best way to help keep your dog and your home flea-free is to use a regular preventative flea treatment.

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Why Advantage®II?
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Up to 28 days of protection
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Kills fleas through contact
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Suitable for use on puppies and dogs
Fight fleas, with ease, with Advantage®II
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Parasites treated with Advantage II for dogs
Fight fleas, with ease, with Advantage®II

The active ingredient in Advantage®II kills fleas through contact, so fleas don’t have to bite your pet to be killed.1 It’s easy to apply, fast and effective and helps protect your dog against fleas for up to four weeks.

How to use Advantage®II

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How to apply Advantage®II step 1: remove collar before application
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Step 1: Remove collar before application.
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Remove one applicator tube from the package, hold it upright and pull the cap off.
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Step 2: Remove one applicator tube from the package, hold it upright and pull the cap off.
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How to apply Advantage®II step 3: Use the reversed cap to pierce and twist off the seal from the tube.
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Step 3: Use the reversed cap to pierce and twist off the seal from the tube.
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How to use Advantage®II step 4: part your dog’s hair, starting at the shoulder blades
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Step 4: Part your dog’s hair, starting at the shoulder blades.
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How to apply Advantage®II step 5: Apply the entire content of the tube evenly to specified spots along your dog’s back between the shoulder blades.
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Step 5: Apply the entire content of the tube evenly to specified spots along your dog’s back between the shoulder blades.
  • For dogs less than 25 kg: With your dog standing, apply the entire tube to one spot on your dog’s back between the shoulder blades.
  • For dogs over 25 kg: With your dog standing, apply the entire contents of the tube evenly to 5 spots along your dog’s back between the shoulder blades.

For all size dogs: do not rub in treatment; allow to dry naturally. It is recommended to keep your dog off leather furniture or wood floors while the product dries.

Make sure you record the treatment date and repeat monthly.

Note: only apply to intact skin. If you’re unsure how to apply Advantage®II, refer to the product information included in the pack or contact your veterinarian. Choose the correct Advantage®II product suitable for your dog’s weight.

About Advantage®II for Dogs
What is the difference between how Advantage®II is applied and kills fleas, compared to oral flea products?

Advantage®II is a topical treatment so it’s applied to your pet’s skin and will kill fleas through contact. It does not require fleas to bite1.

Oral flea products, in contrast, are active in the bloodstream, which means fleas must bite your pet to be killed.

  • 1. Mehlhorn et al. Parasitol Res (2001) 87:198-207, information is regarding mode of action and is not intended to imply parasites can be completely stopped from biting. 
When can I start using Advantage®II on my puppy?

You can use Advantage®II on puppies seven weeks old and over.

Can I use Advantage®II on a pregnant or lactating dog?

Consult your veterinarian before using this product, or any product, on pregnant or lactating dogs

What if I think my pet has a sensitivity to Advantage®II?

Sensitivities may occur after using any pesticide product for pets. If signs persist or become more severe, consult a veterinarian immediately. Call 1 888 663 5326 for assistance regarding product use.

Do I need a prescription from my veterinarian to buy Advantage®II?

Advantage®II is a non-prescription treatment which is available at your pet shop, veterinarian, and online*.

*availability may vary by province

Advantage®II Application
How do I apply Advantage®II?

It’s quick and simple to use Advantage®II, making it a convenient way to treat your pet for fleas year-round. Apply Advantage®II once a month to help protect your pet and home against fleas.

Step 1: Remove your dog’s collar before application.

Step 2: Hold applicator tube upright and pull cap off.

Step 3: Use the opposite end of the cap to break the seal.

Step 4: Part your dog’s hair, starting at the shoulder blades

Step 5: Apply the entire content of the tube evenly to specified spots along your dog’s back between the shoulder blades.

  • for dogs less than 25 kg (under 55 pounds): with your dog standing, apply the entire tube to one spot on your dog’s back between the shoulder blades.
  • for dogs over 25 kg (over 55 pounds): With your dog standing, apply the entire contents of the tube evenly to 5 spots along your dog’s back between the shoulder blades.

For all size dogs: do not rub in treatment; allow to dry naturally.

Make sure you record the treatment date and repeat monthly.

Note: only apply to intact skin. Keep recently treated animals separated so they can’t groom each other. If you’re unsure how to apply Advantage®II, refer to the product information included in the pack or contact your veterinarian. Choose the correct Advantage®II product suitable for your dog’s weight.

How often should I use Advantage®II?

It is recommended that Advantage®II is applied every 4 weeks for the treatment of flea infestations in dogs and the prevention of re-infestation, as well as for the treatment of lice.

How long does Advantage®II last?

A single application lasts for up to four weeks.

Once applied, Advantage®II gets to work quickly. It starts killing fleas within 2 hours2, and within 24 hours all fleas on your dog will be killed.

  • 2. Melhorn, 2000Melhorn, H., 2000. Mode of action of imidacloprid and comparison with other insecticides (i.e. fipronil and selamectin) during in vivo and in vitro experiments. A Supplement to the Compendium for the Continuing Education for Practicing Veterinarian. In: Proceedings of the International Flea Symposium, Vol. 22, No. 4A, pp. 4–8.
Which Advantage®II product is the right one for my dog?

To protect against fleas with Advantage®II, you will need to choose the correct product based on your dog’s weight. Use this guide to find which product is right for your dog:

  • Dogs weighing under 4.5 kg (under 10 pounds) require Advantage®II for Small Dogs 0.4 mL topical solution
  • Dogs weighing between 4.6 kg and 11 kg (10 to 24 pounds) require Advantage®II for Medium Dogs 1 mL topical solution
  • Dogs weighing between 11 kg and 25 kg (24 to 55 pounds) require Advantage®II for Large Dogs 2.5 mL topical solution
  • Dogs over 25 kg (over 55 pounds) require Advantage®II for Extra Large Dogs 4 mL topical solution
What is included with each pack of Advantage®II?

Every pack of Advantage®II contains 4 to 6 single-use tubes.

What is the expiration date for Advantage®II? I can’t find the expiration date on the pack.

Advantage®II does not expire.

My dog spends most of his time indoors. Should I still use Advantage®II topical flea treatment?

Even indoor pets can get fleas. Fleas can be carried into the home on your clothing, or from other pets that visit the house, putting your dog at risk. That’s why it’s still important to regularly protect your dog with a flea product like Advantage®II for dogs.

For households with multiple pets
Can I split tubes of Advantage®II between my dogs?

No, each dog should receive their own dose of Advantage®II.  Always follow the instructions on the packet carefully and give your dog the correct dosage for their weight to ensure effective treatment. If you’re unsure of how to apply Advantage® II, contact your veterinarian. 

I have only seen fleas on one of my pets. Is it sufficient to only treat the infested pet?

It’s important to treat all household pets with the appropriate flea treatment. When one pet has fleas, other pets in the house will soon be infested as well.

Bathing and swimming when using Advantage®II
How long do I need to wait after bathing my dog before I apply Advantage®II flea treatment? 

If you’ve recently bathed your dog, it’s recommended you wait at least two days before applying Advantage®II flea treatment.

When can I bathe my dog after applying Advantage®II? 

It’s recommended that you avoid bathing your dog for at least three days after treatment.

After three days, it’s fine to give your dog a bath in a non-medicated shampoo made for dogs or cats. Baths can be given as often as once per month without affecting the performance of the product. If more than one bath is given, the product should be reapplied after the second bath.

Note: flea shampoo, medicated shampoos, human shampoo and dish detergents are not appropriate choices when managing fleas with Advantage®II as they may affect the performance of the product.

Can I allow my pet to swim when using Advantage®II? 

The active ingredient in Advantage®II sits in the waterproof layer of your dog’s skin and the product remains effective even if your dog becomes wet (for example, after exposure to heavy rain or swimming).  

Can I use Advantage®II for...
Can Advantage®II be used to treat Flea Allergy Dermatitis in my dog? 

Flea Allergy Dermatitis (FAD) is an allergic reaction some dogs suffer from when they come into contact with flea saliva as a result of flea bites. It causes dogs to scratch and bite their skin to relieve the extreme irritation. This can lead to hair loss, irritated skin also known as ‘hot spots’ or nasty infections.

If your vet has diagnosed your dog with Flea Allergy Dermatitis, Advantage®II flea treatment can be used as part of a treatment strategy. The active ingredient in Advantage®II kills fleas through contact, meaning they don’t have to bite your dog in order to be killed. This means dogs are less exposed to the saliva they’re allergic to, helping to reduce FAD outbreaks.

Can I use Advantage®II to treat louse infestations? 

Yes, Advantage®II dog products can be used to treat lice, in addition to fleas. You should book a follow-up with your veterinarian 30 days after treatment, as some dogs may need a second treatment to clear up the louse infestation. 

The FAQs about Fleas
How does my dog get fleas? 

There are several ways fleas can easily invade your home and your pets:

  • If your dog socializes with other dogs when out on a walk, they can easily pick up fleas from their buddies;
  • Your dog can catch them from other household pets. Even if you haven’t noticed your pet cat or rabbit scratching more than usual, they could still have fleas. If they are not treated, they could easily transfer fleas to your dog;
  • Wild animals such as mice and rats, squirrels, groundhogs, rabbits, skunks, raccoons, foxes and coyotes can transport fleas into your backyard or nearby shrubbery, where they can get transferred onto your dog;
  • If you come into contact with fleas yourself, these persistent parasites can hitch a ride on you or your clothing into your home.
How should I treat my home for fleas? 

If your dog does catch fleas, your home can quickly become infested. The fleas lay eggs on your pet, which fall off throughout your home. These eggs hatch into larvae, which develop into pupae and then adult fleas. Fleas, their eggs, larvae and pupae hide in your carpets, bedding and upholstery. They can also take up residence in the upholstery of your car. Once the adult fleas hatch, they are hungry to feed on any red-blooded mammals they can find, including humans.

Advantage®II kills fleas and stops infestations quickly. If you are still seeing fleas on your pet despite using Advantage® II, it’s likely that these are hitchhiker fleas. Once they jump onto your pet, they, too, will be killed by Advantage®II.

You can, however, put a stop to the flea cycle even faster by washing your dog’s bedding in very hot water (and your bedding as well if your pet sleeps with you) and putting it in the dryer, if possible. Vacuuming your carpets and floors at least once a week can also encourage fleas to seek out the protection of your pet – who has already been treated with Advantage® II.

For more in-depth tips about tackling flea infestations, read our essential guide to evicting fleas from your home.

Where can I buy Advantage®II?

Advantage®II is available online, through your veterinarian, and in pet stores.

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L.CA.MKT.AH.02.2020.0508
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Advantage®II Dog Flea Treatment Range